Wed 29 Aug 2007
Red wine 'holds secret to long life'
A study on Resveratrol shows it may have significant anti ageing effects.
Said David Sinclair of Harvard Medical School in Boston, who led the study 'We found this chemical that can extend the life span of every organism we give it to'.
Writing in the Journal Nature, Sinclair and colleagues at the University of Connecticut and Brown University in Rhode Island said they were looking for a compound that would affect the body the way calorie restriction did.
Scientists have learned molecules called Sir2-like proteins or sirtuins, found in creatures ranging from bacteria to humans, are involved in the well known anti-aging effects resulting from calorie restriction.
'We were looking for molecules that would stick to and activate this sirtuin protein' Sinclair said.
'When I realised it was a molecule from red wine I almost fell out of my seat.
This is the molecule people suspect is behind the health benefits of red wine. It's uncanny.'
Sinclair first reported Resveratrol extended the life of yeast fruit flies and tiny worms both of which share many basic biologic processes with humans.
'If you give these compounds to these animals they are healthier and longer-lived, and just as active. They can eat as much as they like and they live considerably longer' said Sinclair.